ThroMbin Receptor-Like 1 (1-6) aMide (Mouse, rat), SLIGRLaMide, Proteinase Activated Receptor 2 (1-6) aMide (Mouse, rat), Coagulation Factor II Receptor-Like 1 (1-6) aMide (Mouse, rat)

Name	H-SER-LEU-ILE-GLY-ARG-LEU-NH2
Synonyms	H2N-SLIGRL-AMIDE PAR2-AP, SLIGRL-NH2 SER-LEU-ILE-GLY-ARG-LEU-NH2 Ser-Leu-Ile-Gly-Arg-Leu-NH2 H-SER-LEU-ILE-GLY-ARG-LEU-NH2 Ser-Leu-Ile-Gly-Arg-Leu-amide trifluoroacetate salt SLIGRL-NH2 Protease-Activated Receptor 2 (PAR2) Agonist COAGULATION FACTOR II RECEPTOR-LIKE 1 (1-6) AMIDE (MOUSE, RAT) ThroMbin Receptor-Like 1 (1-6) aMide (Mouse, rat), SLIGRLaMide, Proteinase Activated Receptor 2 (1-6) aMide (Mouse, rat), Coagulation Factor II Receptor-Like 1 (1-6) aMide (Mouse, rat)
CAS	171436-38-7

Molecular Formula	C29H56N10O7
Molar Mass	656.82
Density	1.34±0.1 g/cm3(Predicted)
Appearance	solid
pKa	12.04±0.10(Predicted)
Storage Condition	-20°C
In vitro study	SLIGRL-NH2 is an agonist of PAR-2 and MrgprC11. SLIGRL-NH2 causes an L-NAME-inhibited relaxation. Based on SLIGRL-NH 2 causing a concentration-dependent relaxation with an EC 50 of 10 µM in endothelium-free preparations in the presence of perivascular adipose tissue (PVAT) , 20 µM is used as a suitable ‘test’ concentration of peptide in subsequent experiments designed to evaluate the effects of potential inhibitors of ADRF release/action. In the endothelium-free aorta preparations, SLIGRL-NH2 causes a concentration-dependent relaxation in preparations only in the presence of PVAT [+PVAT, -ENDO (endothelium)].

Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3

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Product Name: H-SER-LEU-ILE-GLY-ARG-LEU-NH2 Visit Supplier Webpage Request for quotation
CAS: 171436-38-7
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Mobile: 18021002903
QQ: 3008007409

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ThroMbin Receptor-Like 1 (1-6) aMide (Mouse, rat), SLIGRLaMide, Proteinase Activated Receptor 2 (1-6) aMide (Mouse, rat), Coagulation Factor II Receptor-Like 1 (1-6) aMide (Mouse, rat) Request for Quotation